The MIMM team (Magnetic resonance, isotopomics, metabolomics, monitoring) is composed of around 25 persons with complementary expertise in analytical and physical chemistry, particularly in the fields of solution-state nuclear magnetic resonance (NMR) spectroscopy and isotope analysis at natural abundance, and their application to a broad variety of fields such as metabolism, authentication, forensics or reaction monitoring.
With numerous major grants in the recent years (several international programs including two ERC: SUMMIT and DINAMIX and many ANR and regional grants), the MIMM team has become an international leading research group in two major domains:
- fast and high precision quantitative NMR of complex mixtures, with key method developments in ultrafast 2D NMR and more generally fast quantitative multi-dimensional methods, but also in highly accurate quantitative 13C NMR;
- isotopomics, consisting in the accurate measurement of position-specific isotope natural abundance variations, by high precision quantitative NMR and isotope ratio mass spectrometry, with original applications to fields such as metabolism, environment, authentication or forensics.
The MIMM team constantly increases its expertise, in particular with the application of spatially-encoded 2D NMR methods to reaction and process monitoring at high and low field, or their coupling with dissolution dynamic nuclear polarization to increase the sensitivity of quantitative NMR.
A large part of our developments and applications are devoted to metabolomics, as part of our strong commitment in the Corsaire metabolomics core facility and in the MetaboHUB national infrastructure. This metabolomics expertise is also combined with isotopomics, through the development of innovative "all-in-one" methods. The team applications are also available to external customers (industry and academic) through Nantes Université subsidiary, Capacités.