NMR platform

Supported by :

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The NMR platform has strong ties with the internationally renowned MIMM research team, which is expert in the development of NMR methods and their applications for the study of mixtures. The NMR platform serves a broad community of internal and external users. The main users within the CEISAM laboratory are the MIMM team, and the CORAIL, IMF and SYMBIOSE teams, for whom NMR is an indispensable structural characterization tool.

The NMR platform therefore has to address the needs of a broad community, which covers a wide range of topics, ranging from organic synthesis to NMR methodology and metabolomics, while being open to users and external customers. The platform combines instruments for the development and implementation of advanced NMR methods (e.g., cryoprobes, DNP, microimaging) with instruments configured for routine structural analysis in organic synthesis.


CEISAM Plateforme RMN

The NMR platform is also part of the Corsaire platform (multi-site metabolomics platform of the Biogenouest network). In 2020, the NMR platform has joined the MetaboHUB national infrastructure (national metabolomic and fluxomic infrastructure).

In order to work with industrial customers, the NMR platform works closely with the SpectroMaitrisecompany, created by the MIMM team and emanating from CAPACITES SAS (a private valuation subsidiary of the University of Nantes).



▪ For the CEISAM institute

  1. Analytical facility. Structural analyses (routine or targeted), quantitative analyses, molecular dynamics, …
  2. Rasearch. The NMR platform is used for methods developments in NMR, carried out by the MIMM research team. The platform’s staff are members of the MIMM research team.
  3. Management of the instruments. Optimizing the use of spectrometers by improving their performance and allocating instrument time.
  4. Training – support. The platform’s staff supports research teams through: (i) the collection of requests for experiments, (ii) the distribution of these requests among platform team members, (iii) the development and implementation of solutions to these requests.

In all cases, the objective of the platform is to be an active support for the scientific publications of the CEISAM laboratory.


Dans tous les cas, l’objectif de la plateforme est d’être un support actif aux publications scientifiques de l’UMR CEISAM.

▪ For the outdoors

The CEISAM NMR platform is also open to external users, from both industry and academia. Access to the platform is through research collaborations or paid service.

NMR platform staff

Scientific manager:
(Deputies: Vincent COEFFARD and Jean-Nicolas DUMEZ)

Platform engineers:
Aurélie BERNARD, Benoît CHARRIER, Mathilde GRAND, Estelle MARTINEAU, Virginie SILVESTRE

Spectrometers of the CEISAM NMR platform

High-resolution liquid-state NMR spectrometers

Avance HD 700 MHz Bruker

Magnet: Ascend
Probe: reverse CRYO 1H/13C/15N/2H Lock 2H/19F ATMA grad-Z 5mm
Options: 4 canaux, régulation BCU
Sample changer: SampleJet 96 positions
Software: Topspin 3

Avance HD 700 MHz Bruker

Avance III 500 MHz Bruker

Probe: inverse 1H/13C/BB grad-Z 5mm ; micro-imagerie grad-X,Y,Z
Options: 3 canaux, régulation BCU
Sample changer: SampleXpressLite 24
Accessory for Flow NMR
Software: Topspin 2&3 and Paravision

Avance NEO 400 MHz Bruker

Probe: cryo prodigy BBFO ATMA grad 5mm
Software: Topspin 4

Avance NEO 400 MHz Bruker


Bruker d-DNP polariser prototype 7,05 T

Solid-state low temperature probe for DNP with croww-polarization 1H/13C
Magnetic tunnel

Avance III 400 MHz Bruker

Probe: BBFO ATMA grad 5mm ; reverse 1H/BB grad 5 mm ; 1H/BB 10mm
Sample changer: B-ACS 60
Software: Topspin 2

Avance III 400 MHz Bruker

Pulse 400 MHz RS2D

Pulse 400 MHz RS²D
Bruker 7,05 T

Magnet: Bruker
Probes: DUAL+ 1H/13C ATMA grad-Z 5mm ; 1H/2H 10mm, 1H/13C 5mm, 1H/BB 10mm.
Options: 3 canaux.
Sample changer: B-ACS 60.
Software: SPINit

Pulse 300 MHz Bruker

Magnet: US Bruker
Probes: BBFO ATMA grad-Z 5mm, BBO ATMA grad-Z 5mm
Sample changer: SampleXpress 60
Software: Topspin 2

Pulse 300 MHz RS2D

NMR benchtop spectrometers

Spinsolve 43 MHz Magritek

Built-in probe 1H/19F 5 mm, built in fluorine lock. Prototype with Z gradient.
Spinsolve Reaction Monitoring Kit (Pump, capillary…).
Software: Prospa, Spinsolve, Mnova

Spinsolve 43 MHz Magritek

Pulse 400 MHz RS2D

Spinsolve carbone 43 MHz Magritek

Built-in probe : 1H/13C, Fluor 5mm, built in fluorine lock. Prototype with Z gradient.
Spinsolve Reaction Monitoring Kit (Pump, capillary…)
Software: Prospa, Spinsolve, Mnova.

Spinsolve carbone 60 MHz Magritek

Built-in probe: 1H/13C, Fluorine 5mm, built in fluorine lock. Prototype with Z gradient.
Sample changer: 20 samples
Software: Prospa, Spinsolve, Mnova

(This spectrometer belongs to the INPS Lyon but it is currently located in the CEISAM platform)