UPLC-HRMS² high resolution (Waters)

UPLC: Acquity H-Class
MS: ESI-Q-TOF (XEVO G2-XS QTOF)
Analysis: MS, HRMS, MS² as a direct injection or coupled with UPLC
Sources / probe: ESI, APCI / ASAP
Introduction modes: direct / indirect (UPLC)
Nature of the sample: liquid / solid

GC-MS low resolution (Agilent)

GC: 7890B
MS: IE-SQ (MSD5977B)
Analysis:  GC-MS, characterization of small organic molecules using library screening
Source: EI
Introduction mode : indirect (GC)
Nature of the sample: liquid / solid (after dissolution)

Reverse-Phase HPLC (Waters)

HPLC: Alliance e2695
Detection 1: UV-VIS diode array (PDA 2996)
Detection 2: ELSD (ELS 2424)
Detection 3: Multifluorescence Detector (FLR 2475)
Analysis: Molecular characterization, assays, monitoring of organic synthesis

HPLC Chirale (Agilent)

HPLC: 1100 Agilent
Detector 1:  UV-VIS with diode array (Agilent)
Detector 2: Polarimètre OR 2090 (JASCO)
Injection mode : autosampler
Separation mode: chirale, normal phase
Analysis: quantitative analysis of enantiomeric excess, diastereomeric ratios measurement

Screening with 9 chiral columns:

CHIRALPAK AD-H, AS-H, IA, IB, IC
CHIRALCEL OD-H, OJ-H
Lux Amylose-2
Lux Cellulose-4

UPLC dual detection (Waters)

UPLC : Acquity H-Class
Detector 1: ELSD
Detector 2: UV-VIS with diode array
Separation mode: reversed phase, HILIC
Analysis: characterization of molecules, quantitative analysis, monitoring of kinetic reactions

Ion Chromatography (Metrohm)

HPLC: Metrohm 883 Basic IC
Detection: Conductivity
Suppressor: MSM A module
Injection mode: Manual
Analysis: Measurement and quantification of anions and cations down
to the µg/L range

Self-Service HPLC (Agilent)

HPLC: Agilent 1200 Series
Detection: UV-Vis
Injection mode: Manual
Separation mode: Reverse-phase
Analysis: Molecular characterization, monitoring of organic synthesis