CHEM-Symbiose platform – Equipments

PuriFlash 5.030 / expressIon S / plate eXpress - Advion Interchim

Automatic flash purification system
(molecule purification)
Mass detector (1200 Da)
UV/DEDL detector
Sample weight: 4 g to 300 g
Particle size: 15 μm, 40 μm

TLC/MS system
(mass analysis of CCM spots)

Purchase: 2025 – 150 k€ - Funding from Biogenouest/Pays de la Loire/IBiSA/Internal funds

Chemical library Sero’Box - AccsA’Tech

4°C Refrigerator – XXX slots
(storage of synthesized compounds)
Scanner
Barcode label printer

Purchase: 2022 – 12.5 k€ - Funding from Biogenouest, Pays de la Loire, and internal funds

C850 - BUCHI

Automatic flash/preparative purification system
(molecule purification)

UV/DEDL detector

Stationary phases: Silica, C18…

3 pairs of analytical/preparative columns
Sample weight: 4 g to 300 g
Particle size: 15 μm, 40 μm

Purchase: 2020 – 72 k€ - Funding from Biogenouest/Pays de la Loire/IBiSA/Internal funds

HYBRID RC6 - Vacuubrand

High-vacuum pump
(optimal drying of final compounds)
Threshold: 10–3 mbar
Paired with a DIVA® 4-way stainless steel manifold

Purchase: 2018 – 13.3 k€ - Funding from IBiSA

Reveleris X2 - BUCHI

Automatic flash purification system
(molecule purification)
UV/DEDL detector
Sample weight: 4 g to 300 g
Particle size: 15 μm, 40 μm

Purchase: 2015 – 40 k€ - Funding from Biogenouest/Pays de la Loire

Hei-VAP Value - Heidolph

Pair of rotary evaporators
(molecule drying/reaction feedstock)
Pumps: Vacuubrand
Cryostat: Huber

Purchased: 2015 – Internal funds

Currently being acquired:

Scale-up Package: mini-pilot reactor and semi-continuous rotary evaporator (Purchase: 2026 – 85 k€) - Funding from Biogenouest/Pays de la Loire/IBiSA/own funds.

Evaporation Package: refurbishment of the two rotary evaporators (Purchase: 2026 – 18.75 k€) – Funding from Biogenouest/Pays de la Loire/IBiSA/own funds.

Future Acquisition Plans:

Next-generation flash purification unit: upgrade + expansion of the platform through the hiring of a new Assistant Engineer.