AMaCC platform – Equipments

The platform has an area of 125m², including 90m² of laboratories in which all the analytical equipment is distributed. It was financed with the support of:

europe region pdll

The operation CPER "Spectrométrie de masse CEISAM" of the project CISPEO is cofunded by the European Union through the funds of the region Pays de la Loire (FEDER).

UPLC-MS² high resolution (Waters)

UPLC: Acquity H-Class
MS: ESI-Q-TOF (XEVO G2-XS QTOF)
Analysis: MS, mesure de masse exacte (HRMS), MS², UPLC-MS, UPLC-MS²
Sources/probes: ESI/APCI, ASAP
Introduction modes: liquid or solid

LC-MS basse résolution (Waters)

LC-MS low resolution (Waters)

HPLC: Alliance
MS: ESI-SQ (Acquity QDa)
Detector 1: UV-VIS with diode-array (PDA 2996)
Detector 2: Multi-fluorescence detector  (FLD2475)
Analysis: LC-MS, LC-UV/VIS, LC-FLD, dosages, caractérisation de molécules, suivi de cinétique de réaction
Source: ESI

GC-MS low resolution (Agilent)

GC: 7890B
MS: IE-SQ (MSD5977B)
Analysis: GC-MS, library research
Source: EI
Introduction mode : liquid

GC-MS basse résolution (Agilent)

HPLC Chirale (Agilent)

HPLC Chirale (Agilent)

HPLC: 1200 Agilent
Detector 1:  UV-VIS with diode array (Agilent)
Detector 2: Polarimètre OR 2090 (JASCO)
Injection mode : autosampler
Separation mode: chirale, normale phase
Analyses: quantitative analysis of enantiomeric excess, diastereomeric ratios measurement

Screening with 9 chiral columns:

  • CHIRALPAK AD-H, AS-H, IA, IB, IC
  • CHIRALCEL OD-H, OJ-H
  • Lux Amylose-2
  • Lux Cellulose-4

UPLC dual detection (Waters)

UPLC : Acquity H-Class
Detector 1: DEDL
Detector 2: UV-VIS with diode array
Separation mode: reversed phase, HILIC, chiral reversed phase
Analysis: characterization of molecules, quantitative analysis, monitoring of kinetic reactions, quantitative analysis of enantiomeric excesses in reversed phase

UPLC double détection

HPLC (Agilent)

HPLC (Agilent)

HPLC : 1100 Agilent
Detector 1 : UV (Agilent)
Detector 2 : RI (Agilent)
Injection mode: manual
Separation mode: normal phase
Analysis: characterization of molecules, organic synthesis monitoring

2 GC-FID Automatic injection (Agilent)

GC: 7820
Detector: FID
Injection mode: Split/Splitless autosampler
Analysis: characterization of molecules, organic synthesis monitoring, monitoring of kinetic reactions, quantitative analysis

1 GC-TCD (Agilent)

GC: 6890
Detector: TCD
Injection mode: Split/Splitless
Analysis: quantitative analysis of hydrogen, monitoring of kinetic reactions

GC manual injection (Agilent)

GC : 6890
Detector: FID
Injection mode: Split/Splitless
Analysis: characterization of molecules, organic synthesis monitoring, monitoring of kinetic reactions, quantitative analysis